FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Styp\AvrAUAS.Tag:MYC
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General Information
Symbol
Styp\AvrAUAS.Tag:MYC
Species
S. typhimurium
Name
FlyBase ID
FBal0284401
Feature type
allele
Associated gene
Styp\AvrA
Associated Insertion(s)
Carried in Construct
P{UAS-AvrA.myc}
Transgenic product class
wild_type
(Jones et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Jones et al., 2008)
Mutagen
in vitro construct
(Jones et al., 2008)
Progenitor genotype
Carried in construct
P{UAS-AvrA.myc}
Cytology
Description

UAS regulatory sequences drive expression of Styp\AvrA tagged at the N-terminal end with Tag:MYC.

(Jones et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Styp\AvrA
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing Styp\AvrAScer\UAS.T:Hsap\MYC under the control of Scer\GAL4c564 have a greater mortality rate compared to wild type following parenteral Gram-negative infections with E.coli and E.carotovora. Survival rate is similar to wild type following infection with either the Gram-positive bacteria Micrococus luteus or Bauvaria basiana fungal spores.

      Expression of Styp\AvrAScer\UAS.T:Hsap\MYC under the control of Scer\GAL4GMR.PF has no discernible effects on gross appearance of the adult eye or any evidence of cell death.

      (Jones et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of Styp\AvrAScer\UAS.T:Hsap\MYC almost completely suppresses the small eye phenotype seen when Tak1Scer\UAS.cUa is expressed under the control of Scer\GAL4GMR.PF.

      Expression of Styp\AvrAScer\UAS.T:Hsap\MYC completely suppresses the small eye phenotype seen when egrScer\UAS.cUa is expressed under the control of Scer\GAL4GMR.PF.

      Expression of Styp\AvrAScer\UAS.T:Hsap\MYC suppresses the pupal lethality seen in flies co-expressing hepScer\UAS.cUa and bskScer\UAS.cUa under the control of Scer\GAL4GMR.PF. The adult flies exhibit a rough eye phenotype.

      (Jones et al., 2008)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Styp\AvrAScer\UAS.T:Hsap\MYC
      Styp\AvrAUAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)