FB2026_02 , released June 18, 2026
Allele: Dmel\svsev.PS
Open Close
General Information
Symbol
Dmel\svsev.PS
Species
D. melanogaster
Name
sevenless promoter construct of Shi
FlyBase ID
FBal0284793
Feature type
allele
Associated gene
Dmel\sv
Associated Insertion(s)
Carried in Construct
P{sev-sv.S}
Key Links
Transgenic product class
cDNA
(Shi and Noll, 2009)
wild_type
(Shi and Noll, 2009)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Shi and Noll, 2009)
wild_type
(Shi and Noll, 2009)
Mutagen
in vitro construct
(Shi and Noll, 2009)
Progenitor genotype
Carried in construct
P{sev-sv.S}
Cytology
Description

A 2.8 kb KpnI-XbaI fragment obtained from the sv cDNA cpx1, which includes the entire ORF but none of the multiple ployA addition sites, is under the control of GMR regulatory sequences.

(Shi and Noll, 2009)
Allele components
Component
Use(s)
Regulatory region(s)
sev
Encoded product / tool
sv
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      2/13 P{sev-sv.S} lines show a weak rough eye phenotype with one copy, and 9/11 remaining lines show a weak rough eye phenotype with present as 2 copies.

      In svsev.PS/+ pupal eye discs, over 90% of ommatidia have the normal complement of four cone cells, while only 1% contain one additional cone cell.

      (Shi and Noll, 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      svsev.PS has cone cell | pupal stage | increased number phenotype, enhanceable by ttkp88.UAS/Scer\GAL4hs.2sev

      (Shi and Noll, 2009)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      ttkp88.Scer\UAS Scer\GAL4hs.2sev, svsev.PS pupal eye discs have additional cone cells in about 40% of their ommatidia , with a maximum of seven cone cells observed in 1% of the ommatidia.

      One supernumerary cone cell is generated in most ttkp88.Scer\UAS Scer\GAL4hs.2sev, svsev.PS ommatidia, while up to three additional cone cells are generated in only 4% of the ommatidia.

      (Shi and Noll, 2009)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      svsev.PS
      Name Synonyms
      sevenless promoter construct of Shi
      Secondary FlyBase IDs
        References (1)