Imprecise excision of P{GawB}lov91Y resulting in deletion of ~400 bp of DNA downstream of the original insertion, corresponding to intronic/flanking DNA not present in any final lov transcripts.
Approximate boundaries of a 387 bp deletion resulting from the imprecise excison of P{GawB}lov91Y.
egg | maternal effect (with Df(2R)Kr10)
Mutants are viable with normal external adult morphology.
Eggs from homozygous or hemizygous lov66 mothers have a low hatching rate (~20%), irrespective of mating partner genotype. ~80% of the unhatched eggs show no development are are apparently unfertilized. This does not correlate with problems in mating or sperm storage.
Eggs from homozygous or hemizygous lov66 mothers show a range of defects: Class 1 eggs are of normal shape and size, but have a transparent, thin eggshell and dorsal appendages; Class 2 eggs additionally show defects in the final stages of morphogenesis (e.g. aberrant dorsal appendages), often appear unsealed at the anterior, and exhibit incomplete nurse cell dumping; Class 3 eggs are short with sealed eggshells with a cup-shape indentation at the position of the operculum flanked by two stubby dorsal appendages; Class 4 eggs appear normal except for aberrantly shaped dorsal appendages.
During oogenesis in lov66 mothers, defects are observed in vitellogenic and later stages and include malformed dorsal appendages and incomplete nurse cell dumping associated with premature formation of a chorion-like structure between the nurse cells and oocyte.
lov66 larvae grow similarly to controls and show normal behaviour. In uncrowded conditions, homozygous adults emerge in the expected ratio, but the number of emergent adults drops considerably when raised in crowded conditions. Adult climbing behaviour, male courtship and sensory assay performance are essentially normal. In the absence of females, lov66 homozygous males are significantly more active than controls.