FlyBase Allele Report: Dmel\Arfip[UAS.WT]

General Information

Symbol

Dmel\Arfip^UAS.WT

Species

D. melanogaster

Name

FlyBase ID

FBal0285461

Feature type

allele

Associated gene

Dmel\Arfip

Associated Insertion(s)

Carried in Construct

P{UAS-Arfip.WT}

Key Links

Transgenic product class

wild_type

(Chang et al., 2013)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Chang et al., 2013)

Mutagen

in vitro construct

(Chang et al., 2013)

Progenitor genotype

Carried in construct

P{UAS-Arfip.WT}

Cytology

Description

UAS regulatory sequences drive expression of Arfip.

(Chang et al., 2013)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Arfip

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | third instar larval stage, with Scer\GAL4^elav-C155

(Chang et al., 2013)

Phenotype Manifest In

NMJ bouton | increased number | third instar larval stage, with Scer\GAL4^elav-C155

(Chang et al., 2013)

Detailed Description

Statement

Reference

Expression of Arfip^Scer\UAS.WT under the control of Scer\GAL4^elav-C155 results in an increase in the number of boutons at the neuromuscular junction in third-instar larvae.

(Chang et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Arfip^UAS.WT, Scer\GAL4^Toll-6-D42 is an enhancer of abnormal neuroanatomy | third instar larval stage phenotype of DCTN1-p150^Δ.UAS, Scer\GAL4^Toll-6-D42

(Chang et al., 2013)

Phenotype Manifest In

Enhancer of

Statement

Reference

Arfip^UAS.WT, Scer\GAL4^Toll-6-D42 is an enhancer of type Ib terminal bouton | third instar larval stage phenotype of DCTN1-p150^Δ.UAS, Scer\GAL4^Toll-6-D42

(Chang et al., 2013)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of Arfip^Scer\UAS.WT enhances the reduction in the number of type 1b boutons at the neuromuscular junction seen in third-instar larvae expressing Gl^Δ.Scer\UAS under the control of Scer\GAL4^D42.

(Chang et al., 2013)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Arfip^UAS.WT/Scer\GAL4^RapGAP1-OK6 rescues Arfip⁷¹/Arfip¹²

(Chang et al., 2015)

Scer\GAL4^elav-C155/Arfip^UAS.WT rescues Arfip⁷¹/Arfip¹²

(Chang et al., 2013)

Arfip^UAS.WT/Scer\GAL4^RapGAP1-OK6 rescues Arfip⁷¹/Arfip¹²

(Chang et al., 2013)

Comments

Expression of Arfip^Scer\UAS.WT driven by Scer\GAL4^RapGAP1-OK6 rescues the reduced bouton number seen at the neuromuscular junction of Arfip¹²/Arfip⁷¹ third instar larvae.

(Chang et al., 2015)

Expression of Arfip^Scer\UAS.WT under the control of either Scer\GAL4^elav-C155 or Scer\GAL4^Rapgap1-OK6 rescues the reduction in bouton number at the neuromuscular junction seen in Arfip⁷¹/Arfip¹² third instar larvae.

(Chang et al., 2013)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Arfip^Scer\UAS.WT

Arfip^UAS.WT

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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