FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\brkUAS.cDa
Open Close
General Information
Symbol
Dmel\brkUAS.cDa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Doumpas
FlyBase ID
FBal0285464
Feature type
allele
Associated gene
Dmel\brk
Associated Insertion(s)
Carried in Construct
P{UAS-brk.D}
Also Known As
UAS-brk
Key Links
Transgenic product class
wild_type
(Doumpas et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Doumpas et al., 2013)
Mutagen
in vitro construct
(Doumpas et al., 2013)
Progenitor genotype
Carried in construct
P{UAS-brk.D}
Cytology
Description

UAS regulatory sequences drive expression of brk.

(Doumpas et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
brk
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of brkScer\UAS.cDa under the control of Scer\GAL4nub-AC-62 results in adult wings that are significantly reduced in size compared to wild type and which show loss of wing veins.

      (Doumpas et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Scer\GAL4nub-AC-62, brkUAS.cDa has wing phenotype, suppressible | partially by MycUAS.cZa, Scer\GAL4nub-AC-62

      (Doumpas et al., 2013)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of dmScer\UAS.cZa partially suppresses the small wing phenotype caused by expression of brkScer\UAS.cDa under the control of Scer\GAL4nub-AC-62.

      (Doumpas et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      brkScer\UAS.cDa
      brkUAS.cDa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Doumpas
      Secondary FlyBase IDs
        References (3)