FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Hsap\LRRK2UAS.Tag:V5
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General Information
Symbol
Hsap\LRRK2UAS.Tag:V5
Species
H. sapiens
Name
FlyBase ID
FBal0285579
Feature type
allele
Associated gene
Hsap\LRRK2
Associated Insertion(s)
Carried in Construct
PBac{UAS-hLRRK2.WT}
Also Known As
LRRK2WT
Key Links
Transgenic product class
wild_type
(Matta et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Matta et al., 2012)
Mutagen
in vitro construct
(Matta et al., 2012)
Progenitor genotype
Carried in construct
PBac{UAS-hLRRK2.WT}
Cytology
Description

UASt regulatory sequences drive expression of wild-type Hsap\LRRK2 which is tagged with Tag:V5.

(Matta et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\LRRK2
Tagged with
Tag:V5
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Scer\GAL4Toll-6-D42/Hsap\LRRK2UAS.Tag:V5 is a suppressor of autophagosome | third instar larval stage | nutrition conditional phenotype of Lrrke03680

      (Soukup et al., 2016)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      The expression of Hsap\LRRK2Scer\UAS.T:SV5\V5 under the control of Scer\GAL4Toll-6-D42 suppresses the failure of Lrrke03680 homozygotes to exhibit starvation-induced formation of autophagosomes at the third instar larval neuromuscular junction presynaptic region.

      (Soukup et al., 2016)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Hsap\LRRK2Scer\UAS.T:SV5\V5
      Hsap\LRRK2UAS.Tag:V5
      LRRK2WT
      (Soukup et al., 2016, Matta et al., 2012)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)