FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mir-7GS(2)518ND2
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General Information
Symbol
Dmel\mir-7GS(2)518ND2
Species
D. melanogaster
Name
FlyBase ID
FBal0287618
Feature type
allele
Associated gene
Dmel\mir-7
Associated Insertion(s)
P{GSV1}GS(2)518ND2
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{GSV1}GS(2)518ND2
    Cytology
    Description

    The P{GSV1} insertion is 3.1kb upstream of mir-7.

    (Da Ros et al., 2013)
    Allele components
    Component
    Use(s)
    Inserted element
    P{GSV1}
    Regulatory region(s)
    UASt
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Expression of mir-7GS(2)518ND2 in the AP compartment boundary of the wing disc under the control of Scer\GAL4ptc-559.1 results in L3-L4 wing vein fusion.

        Expressing mir-7GS(2)518ND2 under the control of Scer\GAL4ey.PH does not cause any overt eye overgrowth.

        (Da Ros et al., 2013)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhancer of
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        mir-7GS(2)518ND2, Scer\GAL4ey.PH is an enhancer of eye phenotype of DeltaUAS.cDa, Scer\GAL4ey.PH

        (Da Ros et al., 2013)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        mir-7GS(2)518ND2 enhances the eye overgrowth phenotype seen when DlScer\UAS.cDa is expressed under the control of Scer\GAL4ey.PH. Eyes are 250%-320% larger than wild type eyes and the phenotype is seen with 54% penetrance.

        (Da Ros et al., 2013)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        mir-7GS(2)518ND2
        Name Synonyms
        Secondary FlyBase IDs
          References (1)