FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Mmus\Nmnat3UAS.cAa
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General Information
Symbol
Mmus\Nmnat3UAS.cAa
Species
M. musculus
Name
Saccharomyces cerevisiae UAS construct of Avery
FlyBase ID
FBal0288276
Feature type
allele
Associated gene
Mmus\Nmnat3
Associated Insertion(s)
Carried in Construct
P{UAS-Nmnat3.A}
Transgenic product class
cDNA
(Avery et al., 2009)
wild_type
(Avery et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Avery et al., 2009)
wild_type
(Avery et al., 2009)
Mutagen
in vitro construct
(Avery et al., 2009)
Progenitor genotype
Carried in construct
P{UAS-Nmnat3.A}
Cytology
Description

UASt regulatory sequences drive expression of Mmus\Nmnat2 (from cDNA clone BC092086).

(Avery et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Mmus\Nmnat3
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  neurodegenerative disease
      modeled by NmnatJF03337
      (Fang et al., 2012)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Mmus\Nmnat3Scer\UAS.cAa under the control of Scer\GAL4Or22a.8197 protects olfactory receptor neurons from degeneration following axotomy: very few olfactory receptor neuron axons have undergone Wallerian degeneration within five days of injury.

      (Avery et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Mmus\Nmnat3Scer\UAS.cAa
      Mmus\Nmnat3UAS.cAa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct of Avery
      Secondary FlyBase IDs
        References (2)