FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\FsnUAS.Tag:HA
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General Information
Symbol
Dmel\FsnUAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0288301
Feature type
allele
Associated gene
Dmel\Fsn
Associated Insertion(s)
Carried in Construct
P{UAS-Fsn.HA}
Key Links
Transgenic product class
wild_type
(Kugler et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Kugler et al., 2010)
Mutagen
in vitro construct
(Kugler et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-Fsn.HA}
Cytology
Description

UAS regulatory sequences drive expression of Fsn tagged with a Tag:HA epitope.

(Kugler et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Fsn
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos from Scer\GAL4nos.UTR.T:Hsim\VP16>FsnScer\UAS.T:Ivir\HA1-overexpressing females form fewer primordial germ cells than do wild-type embryos (an average of 17 versus 34). Introducing Fsnf06595/+, Df(2R)Exel7124/+ or homozygous Fsnf06595 into the maternal Scer\GAL4nos.UTR.T:Hsim\VP16>FsnScer\UAS.T:Ivir\HA1 overexpression background partially suppresses the loss of primordial germ cells in a statistically significant manner.

      (Kugler et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Suppressor of
      Statement
      Reference

      Scer\GAL4Act5C.PU/FsnUAS.Tag:HA is a suppressor of egg | maternal effect phenotype of gusf07073

      (Kugler et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      vasPH165/+ enhances the primordial germ cell phenotype resulting from the overexpression of Scer\GAL4nos.UTR.T:Hsim\VP16>FsnScer\UAS.T:Ivir\HA1.

      vas1/+ enhances the primordial germ cell phenotype resulting from the overexpression of Scer\GAL4nos.UTR.T:Hsim\VP16>FsnScer\UAS.T:Ivir\HA1.

      Maternal expression of FsnScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4Act5C.PU can partially suppress the gusf07073 collapsed egg phenotype.

      (Kugler et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      FsnScer\UAS.T:Ivir\HA1
      FsnUAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)