FB2026_02 , released June 18, 2026
Allele: Dmel\eIF3m+tVK006
Open Close
General Information
Symbol
Dmel\eIF3m+tVK006
Species
D. melanogaster
Name
FlyBase ID
FBal0288456
Feature type
allele
Associated gene
Dmel\eIF3m
Associated Insertion(s)
Carried in Construct
P{eIF3m+tVK006}
Key Links
Transgenic product class
genomic_DNA
(D'Brot et al., 2013)
wild_type
(D'Brot et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(D'Brot et al., 2013)
wild_type
(D'Brot et al., 2013)
Mutagen
in vitro construct
(D'Brot et al., 2013)
Progenitor genotype
Carried in construct
P{eIF3m+tVK006}
Cytology
Description

A 20kb genomic fragment spanning the Tango7 locus.

(D'Brot et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
eIF3m
Encoded product / tool
eIF3m
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      eIF3m+tVK006 rescues eIF3mL

      (D'Brot et al., 2013)

      eIF3m+tVK006 rescues eIF3mE/eIF3mL

      (D'Brot et al., 2013)

      eIF3m+tVK006 rescues eIF3mE

      (D'Brot et al., 2013)
      Comments

      Expression of Tango7+tVK006 rescues the lethality seen in homozygous Tango7E mutants. Spermatid individualisation also occurs correctly in these flies.

      Expression of Tango7+tVK006 rescues the semi-viability, male sterility and wrinkled wing phenotypes seen in homozygous Tango7L mutants. Spermatid individualisation also occurs correctly.

      Expression of Tango7+tVK006 rescues the semi-viability, male sterility and wrinkled wing phenotypes seen in Tango7L/Tango7E mutants.

      (D'Brot et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Tango7+tVK006
      eIF3m+tVK006
      Name Synonyms
      Secondary FlyBase IDs
        References (1)