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General Information
Symbol
Dmel\rhea15-39
Species
D. melanogaster
Name
FlyBase ID
FBal0288475
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Nucleotide change:

C8568705T

Amino acid change:

Q2052term | rhea-PB; Q2052term | rhea-PC; Q2052term | rhea-PD; Q2052term | rhea-PE; Q2052term | rhea-PF; Q2031term | rhea-PG; Q2052term | rhea-PH

Reported amino acid change:

Q2052term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: Q2052term.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

rhea15-39 mutants exhibit terminal cell pruning with multiple convoluted lumens.

rhea15-39 mutants display dorsal closure and germ band retraction defects.

rhea15-39 dorsal branch terminal cell clones in third instar larvae have ~70% fewer terminal branches than wild-type clones. Most of the rhea15-39 clone terminal cell branches contain a single, smooth, air-filled lumen as in wild-type branches. However, in the tips of some branches, the lumen is convoluted or extra lumens are present.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
Comments
Comments

Based on the extent of the tracheal luminal phenotype, the following rhea alleles can be ranked from weakest to strongest: rhea15-39 < rhea14-69 < rhea6-66 < rhea13-8.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
  • FBal0268687
  • FBal0193597
References (4)