FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\2mitRNAi.UAS.cBa
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General Information
Symbol
Dmel\2mitRNAi.UAS.cBa
Species
D. melanogaster
Name
FlyBase ID
FBal0290450
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat of a 1234bp 2mit cDNA fragment (corresponding to positions 2756-3989 of GenBank:NM_142001.2).

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Males expressing 2mitdsRNA.Scer\UAS.cBa under the control of either Scer\GAL4elav.PU, Scer\GAL4c747 or Scer\GAL4Mef2.247 show a defect in courtship conditioning: the courtship index of homozygous males that have previously courted non-receptive females is not significantly reduced compared to control males that have not undergone conditioning (in contrast to wild-type males, where conditioned males show a reduced courtship index compared to unconditioned controls).

Males expressing 2mitdsRNA.Scer\UAS.cBa under the control of Scer\GAL4ey-OK107 show a defect in courtship conditioning (no significant difference in the courtship index in conditioned and unconditioned males) in two out of three 2mitdsRNA.Scer\UAS.cBa insertion lines studied.

Males expressing 2mitdsRNA.Scer\UAS.cBa under the control of either Scer\GAL4Aph-4-c232 or Scer\GAL452y show normal courtship conditioning (males that have previously courted non-receptive females show a significant reduction in courtship index compared to control males that have not undergone conditioning).

The phase response curve of homozygous flies subjected to 20 light minute pulses at different times during the night is similar to that of wild type.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
2mitRNAi.UAS.cBa
2mitdsRNA.Scer\UAS.cBa
2mitdsRNA.UAS.cBa
Name Synonyms
Secondary FlyBase IDs
    References (2)