FlyBase Allele Report: Dmel\mnb[d419]

General Information

Symbol

Dmel\mnb^d419

Species

D. melanogaster

Name

FlyBase ID

FBal0290884

Feature type

allele

Associated gene

Dmel\mnb

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Hong et al., 2012)

Progenitor genotype

P{EP}mnb^G1767

(Hong et al., 2012)

Cytology

Description

Imprecise excision of the progenitor insertion, resulting in a deletion of mnb sequence.

(Hong et al., 2012)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | dominant | larval stage

(Brown et al., 2024)

decreased size | larval stage

(Yang et al., 2016)

decreased size | P-stage

(Yang et al., 2016)

increased cell death | dominant | larval stage

(Brown et al., 2024)

lethal

(Hong et al., 2012)

lethal - all die before end of P-stage

(Brown et al., 2024)

viable (with Dp(1;3)DC337)

(Brown et al., 2024)

viable (with Dp(1;3)RC033)

(Brown et al., 2024)

viable (with mnb¹)

(Brown et al., 2024)

Phenotype Manifest In

larval brain

(Brown et al., 2024)

larval brain | larval stage

(Yang et al., 2016)

optic lobe neuroepithelial cell | larval stage

(Brown et al., 2024)

pupal brain

(Yang et al., 2016)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

mnb^d419

(Brown et al., 2024, Yang et al., 2016, Hong et al., 2012)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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