FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Lis-1αTub.PD
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General Information
Symbol
Dmel\Lis-1αTub.PD
Species
D. melanogaster
Name
α Tubulin promoter construct of Dix
FlyBase ID
FBal0291054
Feature type
allele
Associated gene
Dmel\Lis-1
Associated Insertion(s)
Carried in Construct
P{αTub-Lis-1.D}
Key Links
Transgenic product class
cDNA
(Dix et al., 2013)
wild_type
(Dix et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Dix et al., 2013)
wild_type
(Dix et al., 2013)
Mutagen
in vitro construct
(Dix et al., 2013)
Progenitor genotype
Carried in construct
P{αTub-Lis-1.D}
Cytology
Description

An αtubulin promoter drives expression of the Lis-1 open reading frame (derived from the LD11219 cDNA).

(Dix et al., 2013)
Allele components
Component
Use(s)
Encoded product / tool
Lis-1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Lis-1αTub.PD rescues Lis-1[+]/Lis-1E415

      (Vagnoni et al., 2016)
      Comments

      Expression of Lis-1αTub.PD suppresses the increased mitochondrial motility observed in Lis-1E415/+ axons in the wing marginal nerve.

      (Vagnoni et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Lis-1αTub.PD
      Name Synonyms
      α Tubulin promoter construct of Dix
      Secondary FlyBase IDs
        References (2)