FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mir-277Ubi-p63E.PZ
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General Information
Symbol
Dmel\mir-277Ubi-p63E.PZ
Species
D. melanogaster
Name
Ubiquitin-63E promoter construct of Zamore
FlyBase ID
FBal0291402
Feature type
allele
Associated gene
Dmel\mir-277
Associated Insertion(s)
Carried in Construct
P{Ubi-p63E-mir-277.Z}
Key Links
Transgenic product class
wild_type
(Esslinger et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Esslinger et al., 2013)
Mutagen
in vitro construct
(Esslinger et al., 2013)
Progenitor genotype
Carried in construct
P{Ubi-p63E-mir-277.Z}
Cytology
Description

A Ubi-p63E promoter drives expression of the mir-277 pre-miRNA hairpin.

(Esslinger et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
Ubi-p63E
Encoded product / tool
mir-277
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies carrying mir-277Ubi-p63E.PZ are short lived compared to controls, on three different food regimes: low sugar/low protein, low sugar/high protein and high sugar/high protein. The short lived phenotype is seen in both males and females.

      (Esslinger et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      chico1, mir-277Ubi-p63E.PZ has lethal phenotype

      (Esslinger et al., 2013)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      chico1/chico1 ; mir-277Ubi-p63E.PZ results in synthetic lethality.

      (Esslinger et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      mir-277Ubi-p63E.PZ
      Name Synonyms
      Ubiquitin-63E promoter construct of Zamore
      Secondary FlyBase IDs
        References (1)