FlyBase Allele Report: Dmel\Optix[KK108290]

General Information

Symbol

Dmel\Optix^KK108290

Species

D. melanogaster

Name

FlyBase ID

FBal0291710

Feature type

allele

Associated gene

Dmel\Optix

Associated Insertion(s)

Carried in Construct

P{KK108290}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK108290}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK108290

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4^ppk.1.9

(Iyer et al., 2013)

visible, with Scer\GAL4^Bx-MS1096

(Schertel et al., 2015)

Phenotype Manifest In

larval dorsal multidendritic neuron ddaC, with Scer\GAL4^ppk.1.9

(Iyer et al., 2013)

larval ventral multidendritic neuron vdaB, with Scer\GAL4^ppk.1.9

(Iyer et al., 2013)

wing, with Scer\GAL4^Bx-MS1096

(Schertel et al., 2015)

Detailed Description

Statement

Reference

Expression of Optix^KK108290 under the control of Scer\GAL4^Bx-MS1096 results in male flies with weak wing size and patterning defects.

Expression of Optix^KK108290 under the control of Scer\GAL4^Bx-MS1096 results in female flies with weak wing size and patterning defects.

(Schertel et al., 2015)

Expression of Optix^KK108290 in C-IV neurons under the control of Scer\GAL4^ppk.1.9 results in a reduction in total dendritic length in ddaC and vdaB neurons. The total number of dendritic branches is also reduced in ddaC neurons.

(Iyer et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v110813

P{KK108290}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Optix^KK108290

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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