FB2026_02 , released June 18, 2026
Allele: Dmel\α-Cat::shgUASp.fl
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General Information
Symbol
Dmel\α-Cat::shgUASp.fl
Species
D. melanogaster
Name
FlyBase ID
FBal0291804
Feature type
allele
Associated gene
α-Cat::shg
Associated Insertion(s)
Carried in Construct
P{UASp-α-Cat::shg.fl}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Pacquelet and Rorth, 2005)
Progenitor genotype
Carried in construct
P{UASp-α-Cat::shg.fl}
Cytology
Description

Full-length α-Cat coding sequences are fused to the carboxy-terminal of full-length shg coding sequences. Expression is driven through UASp regulatory sequences.

(Pacquelet and Rorth, 2005)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
α-Cat::shg
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Scer\GAL4FRT.Rnor\Cd2.αTub84B/α-Cat::shgUASp.fl is a suppressor of epithelial cell | somatic clone phenotype of arm4

      (Pacquelet and Rorth, 2005)

      Scer\GAL4FRT.Rnor\Cd2.αTub84B/α-Cat::shgUASp.fl is a suppressor of cytoskeleton | somatic clone phenotype of arm4

      (Pacquelet and Rorth, 2005)

      Scer\GAL4FRT.Rnor\Cd2.αTub84B/α-Cat::shgUASp.fl is a suppressor of egg chamber phenotype of shgk03401

      (Pacquelet and Rorth, 2005)

      Scer\GAL4FRT.Rnor\Cd2.αTub84B/α-Cat::shgUASp.fl is a suppressor of border follicle cell phenotype of shgk03401

      (Pacquelet and Rorth, 2005)

      Scer\GAL4FRT.Rnor\Cd2.αTub84B/α-Cat::shgUASp.fl is a suppressor of epithelial cell phenotype of shgk03401

      (Pacquelet and Rorth, 2005)

      Scer\GAL4FRT.Rnor\Cd2.αTub84B/α-Cat::shgUASp.fl is a suppressor of nurse cell | somatic clone phenotype of arm4

      (Pacquelet and Rorth, 2005)

      Scer\GAL4FRT.Rnor\Cd2.αTub84B/α-Cat::shgUASp.fl is a suppressor of oocyte | somatic clone phenotype of arm4

      (Pacquelet and Rorth, 2005)

      Scer\GAL4FRT.Rnor\Cd2.αTub84B/α-Cat::shgUASp.fl is a suppressor of border follicle cell | somatic clone phenotype of shgR69

      (Pacquelet and Rorth, 2005)

      Scer\GAL4FRT.Rnor\Cd2.αTub84B/α-Cat::shgUASp.fl is a suppressor of epithelial cell | somatic clone phenotype of shgR69

      (Pacquelet and Rorth, 2005)

      Scer\GAL4FRT.Rnor\Cd2.αTub84B/α-Cat::shgUASp.fl is a suppressor of egg chamber | somatic clone phenotype of shgR69

      (Pacquelet and Rorth, 2005)

      Scer\GAL4FRT.Rnor\Cd2.αTub84B/α-Cat::shgUASp.fl is a suppressor of oocyte phenotype of shgk03401

      (Pacquelet and Rorth, 2005)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of shg::α-CatScer\UAS.fl in follicle cells using the MARCM system and Scer\GAL4Scer\FRT.Rnor\CD2.αTub84B suppresses the follicle cell sorting, loss of epithelial integrity and oocyte mispositioning phenotypes seen in shgR69/+ mutant follicle cell clones. shg::α-CatScer\UAS.fl also fully rescues the migration defects of shg mutant border cells.

      Expression of shg::α-CatScer\UAS.fl in arm4/+ mutant follicle cells using the MARCM system and Scer\GAL4Scer\FRT.Rnor\CD2.αTub84B fully rescues oocyte positioning, sorting, and integrity of follicular epithelia, as well as border cell migration.

      (Pacquelet and Rorth, 2005)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      shg::α-CatScer\UAS.P\T.fl
      shg::α-CatScer\UAS.fl
      α-Cat::shgScer\UAS.P\T.fl
      α-Cat::shgUASp.fl
      Name Synonyms
      Secondary FlyBase IDs
        References (2)