FB2026_03 , released September 17, 2026
Allele: Dmel\shg::MmusCdh1shg.ΔCyt.UASp
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General Information
Symbol
Dmel\shg::Mmus\Cdh1shg.ΔCyt.UASp
Species
D. melanogaster
Name
FlyBase ID
FBal0291807
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Cytology
Description

UASp regulatory sequences drive expression of a fusion protein composed of 'DE-cadherin ΔCyt' (shg lacking the cytoplasmic domain) fused to the Mmus\Cdh1 cytoplasmic domain (amino acids 741-884).

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference

Expression of shg::Mmus\cdh1shgΔC.Scer\UAS.cPa in follicle cells using the MARCM system and Scer\GAL4Scer\FRT.Rnor\CD2.αTub84B suppresses the follicle cell sorting, loss of epithelial integrity and oocyte mispositioning phenotypes seen in shgR69/+ mutant follicle cell clones. In border cells, shg::Mmus\cdh1shgΔC.Scer\UAS.cPa expression rescues shg migration defects.

Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Symbol Synonym
shg::Mmus\Cdh1shg.ΔCyt.UASp
shg::Mmus\Cdh1shgΔC.Scer\UAS.P\T.cPa
shg::Mmus\Cdh1shgΔC.UASp.cPa
shg::Mmus\cdh1shgΔC.Scer\UAS.P\T.cPa
shg::Mmus\cdh1shgΔC.Scer\UAS.cPa
Name Synonyms
Secondary FlyBase IDs
    References (1)