FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\paraDCS-zip
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General Information
Symbol
Dmel\paraDCS-zip
Species
D. melanogaster
Name
FlyBase ID
FBal0293688
Feature type
allele
Associated gene
Dmel\para
Associated Insertion(s)
TI{TI}paraDCS-zip
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
cre recombinase
(Rieder et al., 2013)
ends-out gene targeting
(Rieder et al., 2013)
FLPase
(Rieder et al., 2013)
I-SceI
(Rieder et al., 2013)
Progenitor genotype
Associated Insertion(s)
TI{TI}paraDCS-zip
Cytology
Description

The highly conserved 24 nucleotide 'donor-site complementary sequence' (DCS) has been mutationally extended by 9bp, hypothetically stabilizing the DCS duplex. A 76bp fragment containing a single loxP site is also inserted within para intron 19.

(Rieder et al., 2013)
Allele components
Component
Use(s)
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      para transcripts in paraDCS-zip mutants display cryptic splice donor-site activation within constitutive exon 19 and upstream alternative exon h.

      Homo- or hemi-zygous paraDCS-zip mutants show a significant temperature-sensitive paralytic phenotype.

      (Rieder et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      paraDCS-zip
      Name Synonyms
      Secondary FlyBase IDs
        References (1)