A ubiquitin promoter drives expression of full-length Mmus\Ctnna1.
Scer\GAL4Act.PU, Scer\GAL4da.G32, Mmus\Ctnna1Ubi.PD is a non-suppressor of abnormal cell migration | somatic clone phenotype of α-Cat1
Scer\GAL4Act.PU, Scer\GAL4da.G32, Mmus\Ctnna1Ubi.PD is a non-suppressor of lethal - all die during embryonic stage phenotype of α-Cat1
Scer\GAL4Act.PU, Scer\GAL4da.G32, Mmus\Ctnna1Ubi.PD is a suppressor | partially of follicle cell | somatic clone phenotype of α-Cat1
Scer\GAL4Act.PU, Scer\GAL4da.G32, Mmus\Ctnna1Ubi.PD is a non-suppressor of border follicle cell | somatic clone phenotype of α-Cat1
Scer\GAL4Act.PU, Scer\GAL4da.G32, Mmus\Ctnna1Ubi.PD is a non-suppressor of embryonic head phenotype of α-Cat1
Expression of Mmus\Ctnna1Scer\UAS.P\T.cDa under the control of Scer\GAL4da.G32 and Scer\GAL4Act.PU partially suppresses the follicular epithelium cell phenotypes seen in α-Cat1 mutant follicle cell clones (generated through recombination of the α-CatUbi.PS rescue construct). The border cell migration defects are not rescued.
Ubiquitous expression of Mmus\Ctnna1Scer\UAS.P\T.cDa under the control of Scer\GAL4da.G32 and Scer\GAL4Act.PU fails to rescue the head involution defects seen in α-Cat1 mutant embryos. Animals are unable to live beyond the embryonic stages.