FlyBase Allele Report: Dmel\HDAC3[RNAi.UAS]

General Information

Symbol

Dmel\HDAC3^RNAi.UAS

Species

D. melanogaster

Name

FlyBase ID

FBal0294124

Feature type

allele

Associated gene

Dmel\HDAC3

Associated Insertion(s)

Carried in Construct

P{UAS-HDAC3.RNAi}

Key Links

Transgenic product class

RNAi_reagent

(Pallos et al., 2008)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Pallos et al., 2008)

Mutagen

in vitro construct

(Pallos et al., 2008)

Progenitor genotype

Carried in construct

P{UAS-HDAC3.RNAi}

Cytology

Description

UAS regulatory sequences drive expression of an short hairpin of HDAC3 coding sequence, all within a pWIZ vector.

(Pallos et al., 2008)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

HDAC3

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

HDAC3^RNAi.UAS, Scer\GAL4^elav-C155 is a non-enhancer of abnormal neuroanatomy phenotype of Hsap\HTT^Q93.ex1.UAS, Scer\GAL4^elav-C155

(Pallos et al., 2008)

HDAC3^RNAi.UAS, Scer\GAL4^elav-C155 is a non-enhancer of short lived | calorie restriction conditional phenotype of Hsap\HTT^Q93.ex1.UAS, Scer\GAL4^elav-C155

(Pallos et al., 2008)

NOT Suppressor of

Statement

Reference

HDAC3^RNAi.UAS, Scer\GAL4^elav-C155 is a non-suppressor of abnormal neuroanatomy phenotype of Hsap\HTT^Q93.ex1.UAS, Scer\GAL4^elav-C155

(Pallos et al., 2008)

HDAC3^RNAi.UAS, Scer\GAL4^elav-C155 is a non-suppressor of short lived | calorie restriction conditional phenotype of Hsap\HTT^Q93.ex1.UAS, Scer\GAL4^elav-C155

(Pallos et al., 2008)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

HDAC3^RNAi.UAS, Scer\GAL4^elav-C155 is a non-enhancer of photoreceptor neuron phenotype of Hsap\HTT^Q93.ex1.UAS, Scer\GAL4^elav-C155

(Pallos et al., 2008)

HDAC3^RNAi.UAS, Scer\GAL4^elav-C155 is a non-enhancer of rhabdomere phenotype of Hsap\HTT^Q93.ex1.UAS, Scer\GAL4^elav-C155

(Pallos et al., 2008)

NOT Suppressor of

Statement

Reference

HDAC3^RNAi.UAS, Scer\GAL4^elav-C155 is a non-suppressor of photoreceptor neuron phenotype of Hsap\HTT^Q93.ex1.UAS, Scer\GAL4^elav-C155

(Pallos et al., 2008)

HDAC3^RNAi.UAS, Scer\GAL4^elav-C155 is a non-suppressor of rhabdomere phenotype of Hsap\HTT^Q93.ex1.UAS, Scer\GAL4^elav-C155

(Pallos et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Co-expression of Hdac3^{dsRNA.Scer\UAS} does not affect the level of survival to eclosion or neurodegeneration in flies expressing Hsap\HTT^{Q93.ex1p.Scer\UAS} under the control of Scer\GAL4^elav-C155.

(Pallos et al., 2008)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

HDAC3^RNAi.UAS

HDAC3^{dsRNA.Scer\UAS}

HDAC3^dsRNA.UAS

Hdac3^{dsRNA.Scer\UAS}

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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