GPHR^k34 larval escapers survive through the pupal stage to give rise to pharate adults that are significantly smaller and lighter than control animals. While GPHR^k34 mutant and wild-type larvae grow equally until late mid-L3 stage (96 hr after egg deposition), GPHR^k34 mutant larvae show growth deceleration at late L3. By late L3 and pupal stages, size differences between wild-type and mutant siblings are obvious. In addition, the onset of both pupariation and adult emergence are delayed in GPHR^k34 mutants.

Both cell size and number are reduced in GPHR^k34 homozygous and GPHR^k34/Df(2R)ED2426 mutant adult wing blades.

GPHR^k34 homozygous mutant mitotic wing imaginal disc clones grow and divide to clones of a similar size as wild-type clones. These cells do not show differences in cell division or size, compared to controls. Although GPHR^k34 mutant larvae (120 hrs after egg deposition) display salivary gland cells with reduced nuclei size when compared to controls, no obvious differences in nuclei size are observed between GPHR^k34 mutant MARCM salivary gland cell clones and wild-type cells.

GPHR^k34 mutants exhibit severe endoplasmic reticulum and Golgi disorganisation.