FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\GPHRUAS.cCa
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General Information
Symbol
Dmel\GPHRUAS.cCa
Species
D. melanogaster
Name
FlyBase ID
FBal0294786
Feature type
allele
Associated gene
Dmel\GPHR
Associated Insertion(s)
Carried in Construct
P{UAS-GPHR.c}
Key Links
Transgenic product class
wild_type
(Charroux and Royet, 2014)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Charroux and Royet, 2014)
Mutagen
in vitro construct
(Charroux and Royet, 2014)
Progenitor genotype
Carried in construct
P{UAS-GPHR.c}
Cytology
Description

UASt regulatory sequences drive expression of wild-type GPHR coding sequences.

(Charroux and Royet, 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
GPHR
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4da.G32/GPHRUAS.cCa rescues GPHRk34

      (Charroux and Royet, 2014)

      Scer\GAL4elav-C155/GPHRUAS.cCa rescues GPHRk34

      (Charroux and Royet, 2014)

      Scer\GAL4c601/GPHRUAS.cCa rescues GPHRk34

      (Charroux and Royet, 2014)
      Fails to rescue

      Scer\GAL4Mef2.PR/GPHRUAS.cCa fails to rescue GPHRk34

      (Charroux and Royet, 2014)
      Comments

      Ubiquitous, neuronal or gut expression of GPHRScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4da.G32 is sufficient to fully rescue the growth defects and developmental lethality seen in GPHRk34 mutants. Muscle expression (under the control of Scer\GAL4Mef2.PR does not rescue.

      (Charroux and Royet, 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      GPHRScer\UAS.cCa
      GPHRUAS.cCa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)