FlyBase Allele Report: Dmel\Act42A[UAS.Tag:MYC]

General Information

Symbol

Dmel\Act42A^UAS.Tag:MYC

Species

D. melanogaster

Name

FlyBase ID

FBal0294952

Feature type

allele

Associated gene

Dmel\Act42A

Associated Insertion(s)

Carried in Construct

P{UAS-myc.Act42A}

Key Links

Transgenic product class

wild_type

(Hsiao et al., 2014)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Hsiao et al., 2014)

Mutagen

in vitro construct

(Hsiao et al., 2014)

Progenitor genotype

Carried in construct

P{UAS-myc.Act42A}

Cytology

Description

UAS regulatory sequences drive expression of Act42A coding sequences tagged at the N-terminal with Tag:MYC.

(Hsiao et al., 2014)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Act42A

Tagged with

Tag:MYC

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

macrochaeta | ectopic, with Scer\GAL4^dpp.blk1

(Hsiao et al., 2014)

Detailed Description

Statement

Reference

Expression of Act5C^{Scer\UAS.T:Hsap\MYC} along the boundary of the scutellum, under the control of Scer\GAL4^dpp.blk1, promotes the formation of ectopic bristles in 16.3% of flies. These ectopic bristles are always located near the original bristles, suggesting that they are derived from ac- and sc-expressing proneural clusters.

(Hsiao et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

Act42A^UAS.Tag:MYC, Scer\GAL4^dpp.blk1 is an enhancer of external sensory organ | ectopic phenotype of Scer\GAL4^dpp.blk1, ac^UAS.cUa

(Hsiao et al., 2014)

Act42A^UAS.Tag:MYC, Scer\GAL4^dpp.blk1 is an enhancer of scutellum phenotype of Scer\GAL4^dpp.blk1, ac^UAS.cUa

(Hsiao et al., 2014)

Act42A^UAS.Tag:MYC, Scer\GAL4^dpp.blk1 is an enhancer of wing vein L3 phenotype of Scer\GAL4^dpp.blk1, ac^UAS.cUa

(Hsiao et al., 2014)

NOT Suppressor of

Statement

Reference

Act42A^UAS.Tag:MYC, Scer\GAL4^dpp.blk1 is a non-suppressor of external sensory organ | ectopic phenotype of Scer\GAL4^dpp.blk1, ac^UAS.cUa

(Hsiao et al., 2014)

Act42A^UAS.Tag:MYC, Scer\GAL4^dpp.blk1 is a non-suppressor of scutellum phenotype of Scer\GAL4^dpp.blk1, ac^UAS.cUa

(Hsiao et al., 2014)

Act42A^UAS.Tag:MYC, Scer\GAL4^dpp.blk1 is a non-suppressor of wing vein L3 phenotype of Scer\GAL4^dpp.blk1, ac^UAS.cUa

(Hsiao et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of Act5C^{Scer\UAS.T:Hsap\MYC} does not significantly increase the number of ES organs induced by overexpression of ac^Scer\UAS.cUa.

(Hsiao et al., 2014)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Act42A^UAS.Tag:MYC

Act5C^{Scer\UAS.T:Hsap\MYC}

Act5C^UAS.Tag:MYC

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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