FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Act42AUAS.Tag:MYC,Tag:NLS(SV40-largeT)
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General Information
Symbol
Dmel\Act42AUAS.Tag:MYC,Tag:NLS(SV40-largeT)
Species
D. melanogaster
Name
FlyBase ID
FBal0294953
Feature type
allele
Associated gene
Dmel\Act42A
Associated Insertion(s)
Carried in Construct
P{UAS-myc.nls.Act42A}
Key Links
Transgenic product class
wild_type
(Hsiao et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Hsiao et al., 2014)
Mutagen
in vitro construct
(Hsiao et al., 2014)
Progenitor genotype
Carried in construct
P{UAS-myc.nls.Act42A}
Cytology
Description

UAS regulatory sequences drive expression of Act42A coding sequences tagged at the N-terminal with Tag:MYC and a nuclear localization signal (Tag:NLS(SV40-largeT)).

(Hsiao et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Act42A
Tagged with
Tag:MYC
Tag:NLS(SV40-largeT)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Act5CScer\UAS.T:Hsap\MYC,T:SV40\nls2 along the boundary of the scutellum, under the control of Scer\GAL4dpp.blk1, promotes the formation of ectopic bristles in 27.7% of flies.

      (Hsiao et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Over-expression of Act5CScer\UAS.T:Hsap\MYC,T:SV40\nls2 significantly increases the number of ES organs by 19% in flies expressing acScer\UAS.cUa under the control of Scer\GAL4dpp.blk1.

      (Hsiao et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Act42AUAS.Tag:MYC,Tag:NLS(SV40-largeT)
      Act5CScer\UAS.T:Hsap\MYC,T:SV40\nls-largeT
      Act5CScer\UAS.T:Hsap\MYC,T:SV40\nls2
      Act5CUAS.Tag:MYC,Tag:NLS(SV40-largeT)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)