FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Mkp3UAS.Tag:MYC
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General Information
Symbol
Dmel\Mkp3UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0294973
Feature type
allele
Associated gene
Dmel\Mkp3
Associated Insertion(s)
Carried in Construct
P{UAS-Mkp3.MYC}
Key Links
Transgenic product class
cDNA
(Molnar and de Celis, 2013)
wild_type
(Molnar and de Celis, 2013)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Molnar and de Celis, 2013)
wild_type
(Molnar and de Celis, 2013)
Mutagen
in vitro construct
(Molnar and de Celis, 2013)
Progenitor genotype
Carried in construct
P{UAS-Mkp3.MYC}
Cytology
Description

UAS regulatory sequences drive expression of Mkp3 cDNA tagged at the C-terminal end with 6xTag:MYC.

(Molnar and de Celis, 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Mkp3
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Mkp3Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4salm.EPv results in wing vein loss.

      (Molnar and de Celis, 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhanced by
      NOT suppressed by
      Phenotype Manifest In
      NOT Enhanced by
      NOT suppressed by
      Statement
      Reference

      Mkp3UAS.Tag:MYC, Scer\GAL4salm.EPv has wing vein phenotype, non-suppressible by tayEP-866, Scer\GAL4salm.EPv

      (Molnar and de Celis, 2013)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of tayEP-866 does not modify the wing vein loss phenotype seen when Mkp3Scer\UAS.T:Hsap\MYC is expressed under the control of Scer\GAL4salm.EPv.

      (Molnar and de Celis, 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Mkp3Scer\UAS.T:Hsap\MYC
      Mkp3UAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)