FB2026_02 , released June 18, 2026
Allele: Dmel\Ino80ex64
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General Information
Symbol
Dmel\Ino80ex64
Species
D. melanogaster
Name
FlyBase ID
FBal0295028
Feature type
allele
Associated gene
Dmel\Ino80
Associated Insertion(s)
P{?EPgy2}Ino80ex64
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Neuman et al., 2014)
Progenitor genotype
P{EPgy2}Ino80EY09251
(Neuman et al., 2014)
Associated Insertion(s)
P{?EPgy2}Ino80ex64
Caused by aberration
Df(3R)Ino80ex64
Cytology
Description

Imprecise excision of the P{EPgy2}Ino80EY09251 progenitor insertion, resulting in a large deletion of approximately 20kb, which extends distally from the original insertion site and removes several other genes located within introns of Ino80.

(Neuman et al., 2014)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ino80ex64/Df(3R)ED5942 animals have a persistant salivary gland phenotype (83.7% penetrance) at 24 hours after puparium formation (APF).

      (Neuman et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Ino80ex64 is rescued by Ino80hs.PN

      (Neuman et al., 2014)

      Ino80ex64/Df(3R)ED5942 is rescued by Ino80hs.PN

      (Neuman et al., 2014)
      Comments

      Leaky expression of Ino80hs.PN is able to rescue both the lethality and sterility observed in homozygous Df(3R)Ino80ex64 and Df(3R)Ino80ex64/Df(3R)ED5942 animals.

      (Neuman et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Ino80ex64
      (Neuman et al., 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)