FB2026_03 , released September 17, 2026
Allele: Dmel\gsb-ndb
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General Information
Symbol
Dmel\gsb-ndb
Species
D. melanogaster
Name
FlyBase ID
FBal0295037
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Mutagen
Nature of the Allele
Caused by aberration
Cytology
Description

Deletion extending from intron 3 of gsb-n to approximately 2.5kb upstream of the gsb transcription start site, which is replaced by an insertion and combined with point mutations resulting in two consecutive stop codons after amino acid residue 84 of gsb. Transcription of gsb is unlikely as its enhancers are located within the deleted portion, but the stop codons ensure that any RNA can only be translated into a non-functional gsb protein. This deletion was generated by Scer\FRT-mediated recombination between PBac{WH}gsb-nf06670 and an intermediate product of gsb ends-in homologous recombination (which contained an Scer\FRT site between the proximal wild-type and distal mutated copy of gsb generated by the homologous recombination event).

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
gsb-ndb
Name Synonyms
Secondary FlyBase IDs
    References (1)