FB2026_03 , released September 17, 2026
Allele: Dmel\subduedKO
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General Information
Symbol
Dmel\subduedKO
Species
D. melanogaster
Name
FlyBase ID
FBal0295152
Feature type
allele
Associated gene
Dmel\subdued
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
FLPase
(Wong et al., 2013)
Progenitor genotype
PBac{RB}subduede02779
(Wong et al., 2013)
P{XP}subduedd03361
(Wong et al., 2013)
Caused by aberration
Df(3R)subduedKO
Cytology
Description

Deletion of sequences between the insertion sites of the progenitor insertions, resulting in loss of most of the subdued coding region and part of the CG34138 coding region.

(Wong et al., 2013)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:19,635,431..19,641,276 [-]
Comment:

Deletion of most of the subdued coding region and part of CG34138 resulting from FLP-catalyzed recombination using the FRT-containing transposons PBac{RB}subduede02779 and P{XP}subduedd03361.

(Wong et al., 2013)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Upon being fed the Db11 strain of the bacterium Serratia marcescens, subduedKO flies show significantly higher lethality compared to wild type controls. Mutant flies do not show prominent structural abnormalities in the alimentary canal. Significantly higher titres of bacteria are isolated from infected mutant flies (both whole flies and isolated guts) compared to controls - this is not due to increased feeding by the mutants as the mutants feed slightly, but significantly, less than controls.

      (Wong et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      KO11
      (Wong et al., 2013)
      KO2
      (Wong et al., 2013)
      SubduedKO11
      (Jaszczak et al., 2022)
      SubduedKO2
      (Jaszczak et al., 2022)
      subduedKO
      Name Synonyms
      Secondary FlyBase IDs
        References (2)