FB2026_02 , released June 18, 2026
Allele: Dmel\ligt12
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General Information
Symbol
Dmel\ligt12
Species
D. melanogaster
Name
FlyBase ID
FBal0295156
Feature type
allele
Associated gene
Dmel\lig
Associated Insertion(s)
Carried in Construct
M{Glig.FS}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Baumgartner et al., 2013)
Progenitor genotype
Carried in construct
M{Glig.FS}
Cytology
Description

A genomic construct of lig, based on P{Glig}, that lacks a nucleotide in exon 10 leading to a frameshift (FS) mutation and a premature stop.

(Baumgartner et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
lig
Encoded product / tool
lig
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      ligt12 fails to rescue lig1

      (Baumgartner et al., 2013)

      ligt12 fails to rescue lig2

      (Baumgartner et al., 2013)

      ligt12 fails to rescue lig3

      (Baumgartner et al., 2013)
      Comments

      lig+t12 rescues the lethality and clonal overgrowth phenotype associated with lig1, lig2 and lig3.

      (Baumgartner et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ligt12
      Name Synonyms
      Secondary FlyBase IDs
        References (1)