Open Close
General Information
Symbol
Dmel\rkpan.GAL4
Species
D. melanogaster
Name
FlyBase ID
FBal0295410
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
RkPAN-Gal4
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

The "T2A" peptide from Thosea asigna followed by the Scer\GAL4 coding region has been inserted within exon 14 of rk within the CH322-119A8 Pacman genomic clone that contains the complete rk locus. Exon 14 is shared by all predicted rk splice variants. The insertion of this sequence results in a non-functional truncated rk protein being produced. The "T2A" peptide supports ribosomal skipping, allowing the Scer\GAL4 protein to be translated independently of the upstream rk protein sequences, resulting in functional Scer\GAL4 protein being expressed under the control of rk regulatory sequences.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to rescue
Comments

rkpan.GAL4 fails to rescue the wing expansion defects of rk4 mutant flies.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
rkpan.GAL4
Name Synonyms
Secondary FlyBase IDs
    References (2)