FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Rpt1P1
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General Information
Symbol
Dmel\Rpt1P1
Species
D. melanogaster
Name
FlyBase ID
FBal0295426
Feature type
allele
Associated gene
Dmel\Rpt1
Associated Insertion(s)
P{?lacW}Rpt1P1
Carried in Construct
Key Links
Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(Szabó et al., 2007)
Mutagen
Delta2-3 transposase
(Szabó et al., 2007)
Progenitor genotype
P{lacW}Rpt1k11110
(Szabó et al., 2007)
Associated Insertion(s)
P{?lacW}Rpt1P1
Cytology
Description

Imprecise excision of the P{lacW}Rpt1k11110 progenitor insertion. 32bp of residual P-element sequence remains.

(Szabó et al., 2007)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      Rpt1P1 is rescued by Rpt1Ubi-p63E.PS

      (Szabó et al., 2007)
      Comments

      Expression of Rpt1Ubi-p63E.PS rescues the lethality of Rpt1P1 homozygotes. The rescued flies are fully viable and fertile.

      (Szabó et al., 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      The residual P{?lacW}Rpt1P1 insertion is within Rpt1, which is located within a long intron of CG17985. Homozygosity for the P{?lacW}Rpt1P1 chromosome results in pupal lethality which is rescued by expression of Rpt1Ubi-p63E.PS, indicating that the lethality of the P{?lacW}Rpt1P1 chromosome is due to an effect on Rpt1 alone and not CG17985.

      (Szabó et al., 2007)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      P1
      (Szabó et al., 2007)
      Rpt1P1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)