FlyBase Allele Report: Dmel\Tre1[Δ22]

General Information

Symbol

Dmel\Tre1^Δ22

Species

D. melanogaster

Name

FlyBase ID

FBal0295437

Feature type

allele

Associated gene

Dmel\Tre1

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

hypomorphic allele - molecular evidence

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

hypomorphic allele - molecular evidence

(Rollmann et al., 2006)

Mutagen

Delta2-3 transposase

(Rollmann et al., 2006)

Progenitor genotype

P{GT1}BG01272^BG01272

(Rollmann et al., 2006)

Caused by aberration

Df(1)Δ22

Cytology

Description

Imprecise excision of the progenitor P{GT1}BG01272^BG01272 insertion resulting in a deletion of approximately 2.0kb. Expression of Gr5a is abolished, while expression of Tre1 is reduced.

(Rollmann et al., 2006)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Gr5a^Δ22, Tre1^Δ22 has short lived | female phenotype

(Rollmann et al., 2006)

Gr5a^Δ22, Tre1^Δ22 has abnormal heat stress response | female phenotype

(Rollmann et al., 2006)

Gr5a^Δ22, Tre1^Δ22 has short lived | male phenotype

(Rollmann et al., 2006)

Gr5a^Δ22, Tre1^Δ22 has abnormal chemosensory behavior phenotype

(Rollmann et al., 2006)

Gr5a^Δ22, Tre1^Δ22 has abnormal heat stress response | male phenotype

(Rollmann et al., 2006)

Gr5a^Δ22, Tre1^Δ22 has abnormal starvation stress response | female phenotype

(Rollmann et al., 2006)

Gr5a^Δ22, Tre1^Δ22 has abnormal starvation stress response | male phenotype

(Rollmann et al., 2006)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Df(1)Δ22 flies show a dramatically reduced preference for trehalose compared to controls. Resistance to starvation, resistance to heat-stress and lifespan are significantly decreased compared to controls in both males and females.

(Rollmann et al., 2006)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Tre1^Δ22

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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