FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Disc\RFPmCherry.ppk29.3'UTR.UAS
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General Information
Symbol
Disc\RFPmCherry.ppk29.3'UTR.UAS
Species
D. sp.
Name
FlyBase ID
FBal0295774
Feature type
allele
Associated gene
Disc\RFP
Associated Insertion(s)
Carried in Construct
P{UAS-mCherry.ppk29-3'UTR}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Zheng et al., 2014)
Progenitor genotype
Carried in construct
P{UAS-mCherry.ppk29-3'UTR}
Cytology
Description

UASt regulatory sequences drive expression of mCherry followed by the ppk29 3'UTR from cDNA clone IP06558.

(Zheng et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
mCherry
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing Disc\RFPmCherry.ppk29.3'UTR under the control of Scer\GAL4elav-C155 show more rapid paralysis in response to acute heat stress than wild-type controls.

      Flies expressing Disc\RFPmCherry.ppk29.3'UTR under the control of Scer\GAL4elav.Switch.PO during the adult stage only (using RU486 to control the timing of expression) show more rapid paralysis in response to acute heat stress than wild-type controls.

      (Zheng et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      Disc\RFPmCherry.ppk29.3'UTR.UAS, Scer\GAL4elav-C155 has paralytic | adult stage | heat sensitive phenotype, suppressible by Dcr-2UAS.cDa, Scer\GAL4elav-C155

      (Zheng et al., 2014)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      The more rapid paralysis in response to acute heat stress seen in flies expressing Disc\RFPmCherry.ppk29.3'UTR under the control of Scer\GAL4elav-C155 is suppressed if they are also co-expressing Dcr-2Scer\UAS.cDa.

      (Zheng et al., 2014)
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4elav-C155/Disc\RFPmCherry.ppk29.3'UTR.UAS partially rescues ppk29f06838

      (Zheng et al., 2014)
      Comments

      The increased time to total paralysis in response to heat stress which is seen in ppk29f06838 flies is partially rescued by expression of Disc\RFPmCherry.ppk29.3'UTR under the control of Scer\GAL4elav-C155.

      (Zheng et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Disc\RFPmCherry.ppk29.3'UTR.UAS
      Disc\RFPmCherry.ppk29.3'UTR
      Name Synonyms
      Secondary FlyBase IDs
        References (1)