FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Hmr+t9.5
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General Information
Symbol
Dmel\Hmr+t9.5
Species
D. melanogaster
Name
FlyBase ID
FBal0296129
Feature type
allele
Associated gene
Dmel\Hmr
Associated Insertion(s)
Carried in Construct
P{Hmr.+t9.5}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Thomae et al., 2013)
wild_type
(Thomae et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Thomae et al., 2013)
wild_type
(Thomae et al., 2013)
Mutagen
in vitro construct
(Thomae et al., 2013)
Progenitor genotype
Carried in construct
P{Hmr.+t9.5}
Cytology
Description

9.5kb genomic fragment which contains the entire Hmr gene, and portions of the flanking CG2124 and Rab9D genes.

(Thomae et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
Hmr
Encoded product / tool
Hmr
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
X:10,587,539..10,597,076 [-]
Comment:

A 9.5kb genomic fragment which contains the entire Hmr gene, and portions of the flanking CG2124 and Rab9D genes.

(Lukacs et al., 2021)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      A single autosomal copy of Hmr+t9.5 results in complete lethality of the hybrid female offspring of a cross between D. melanogaster females and D. simulans males.

      (Thomae et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Hmr+t9.5 rescues HmrEY12237

      (Thomae et al., 2013)
      Comments

      The suppression by HmrEY12237 of hybrid male lethality in the progeny of a cross between D. melanogaster females and D. simulans males is no longer seen if the female D. melanogaster parent is also carrying a copy of Hmr+t9.5.

      (Thomae et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Hmr+t9.5
      (Thomae et al., 2013)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)