FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\fruΔAmyc
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General Information
Symbol
Dmel\fruΔAmyc
Species
D. melanogaster
Name
FlyBase ID
FBal0296341
Feature type
allele
Associated gene
Dmel\fru
Associated Insertion(s)
TI{TI}fruΔAmyc
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
gene targeting by homologous recombination
(von Philipsborn et al., 2014)
Progenitor genotype
Associated Insertion(s)
TI{TI}fruΔAmyc
Cytology
Description

A Tag:MYC tag and a stop codon have been inserted after codon G816 in the A exon of fru (FBpp0083063), thereby deleting codons for the final 139 residues of the fru A isoform.

(von Philipsborn et al., 2014)
Allele components
Component
Use(s)
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      fruΔA.T:Hsap\MYC/fruF males show significantly reduced copulation success compared to controls in single-pair courtship assays.

      fruΔA.T:Hsap\MYC/fruF males show courtship song defects: the interpulse interval of the pulse song is longer and more varied than normal, the carrier frequency of sine song is increased and the carrier frequency of pulse song is reduced.

      fruΔA.T:Hsap\MYC/fruF males show no significant change in the number of pMP4/P1, pIP10, dPR1, vPR1, vPR6, aDT2/mAL, aSP1 and aSP2 neuronal cells per hemisphere compared to fru[+] males.

      (von Philipsborn et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      The overall mating ability in competitive mating assays can be ranked as follows: fru[+] > fruΔA.T:Hsap\MYC > fruB2 > fruC1.

      (von Philipsborn et al., 2014)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      FruΔAmyc
      (von Philipsborn et al., 2014)
      fruA
      (von Philipsborn et al., 2014)
      fruΔA.T:Hsap\MYC
      fruΔAmyc
      Name Synonyms
      Secondary FlyBase IDs
        References (1)