FlyBase Allele Report: Drer\ssrp1a[1-518.UAS.Tag:V5]

General Information

Symbol

Drer\ssrp1a^{1-518.UAS.Tag:V5}

Species

D. rerio

Name

FlyBase ID

FBal0296408

Feature type

allele

Associated gene

Drer\ssrp1a

Associated Insertion(s)

Carried in Construct

P{UAS-Zssrp1a.1-518}

Transgenic product class

inframe_deletion

(Koltowska et al., 2013)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

inframe_deletion

(Koltowska et al., 2013)

Mutagen

in vitro construct

(Koltowska et al., 2013)

Progenitor genotype

Carried in construct

P{UAS-Zssrp1a.1-518}

Cytology

Description

UAS regulatory sequences drive expression of Drer\ssrp1b coding sequences corresponding to amino acid residues 1-518.

(Koltowska et al., 2013)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Drer\ssrp1a

Tagged with

Tag:V5

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of Drer\ssrp1a^{1-518.Scer\UAS.T:SV5\V5} under the control of Scer\GAL4^Act5C.PI results in wild-type flies.

(Koltowska et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Drer\ssrp1a^{1-518.UAS.Tag:V5}, Scer\GAL4^Act5C.PI is a suppressor of lethal - all die during pharate adult stage phenotype of Scer\GAL4^Act5C.PI, Ssrp^JF02120

(Koltowska et al., 2013)

Phenotype Manifest In

Suppressor of

Statement

Reference

Drer\ssrp1a^{1-518.UAS.Tag:V5}, Scer\GAL4^Act5C.PI is a suppressor of eye phenotype of Scer\GAL4^Act5C.PI, Ssrp^JF02120

(Koltowska et al., 2013)

Drer\ssrp1a^{1-518.UAS.Tag:V5}, Scer\GAL4^Act5C.PI is a suppressor of antenna phenotype of Scer\GAL4^Act5C.PI, Ssrp^JF02120

(Koltowska et al., 2013)

Drer\ssrp1a^{1-518.UAS.Tag:V5}, Scer\GAL4^Act5C.PI is a suppressor of adult head capsule phenotype of Scer\GAL4^Act5C.PI, Ssrp^JF02120

(Koltowska et al., 2013)

Drer\ssrp1a^{1-518.UAS.Tag:V5}, Scer\GAL4^Act5C.PI is a suppressor of eye-antennal disc phenotype of Scer\GAL4^Act5C.PI, Ssrp^JF02120

(Koltowska et al., 2013)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Co-expression of Drer\ssrp1a^{1-518.Scer\UAS.T:SV5\V5} with Ssrp^JF02120, under the control of Scer\GAL4^Act5C.PI, rescues the severe defects found in developing flies expressing Ssrp^JF02120. Adults of these mutants exhibit slightly rough eyes. Proliferation and R-cell differentiation in eye-antennal discs are indistinguishable from controls.

(Koltowska et al., 2013)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Drer\ssrp1a^{1-518.Scer\UAS.T:SV5\V5}

Drer\ssrp1a^{1-518.UAS.Tag:V5}

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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