FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\otk2C26
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General Information
Symbol
Dmel\otk2C26
Species
D. melanogaster
Name
FlyBase ID
FBal0297443
Feature type
allele
Associated gene
Dmel\otk2
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Linnemannstöns et al., 2014)
Mutagen
FLPase
(Linnemannstöns et al., 2014)
Progenitor genotype
Cytology
Description

FLP-induced excision of PBac{PB}Mppec01790 and P{XP}d01360 removes the otk coding region.

(Linnemannstöns et al., 2014)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      otk2C26 homozygotes have no discernable phenotype.

      (Ripp et al., 2018)

      otk2C26 mutants do not display defects in planar cell polarity in their wings and eyes. There do not appear to be any patterning defects in the embryonic cuticle.

      (Linnemannstöns et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      Statement
      Reference

      otk2C26/otk2C26 is a non-enhancer of viable phenotype of Ror4

      (Ripp et al., 2018)

      otk2C26/otk2C26 is a non-enhancer of fertile phenotype of Ror4

      (Ripp et al., 2018)
      NOT Suppressor of
      Statement
      Reference

      otk2C26/otk2C26 is a non-suppressor of viable phenotype of Ror4

      (Ripp et al., 2018)

      otk2C26/otk2C26 is a non-suppressor of fertile phenotype of Ror4

      (Ripp et al., 2018)
      Other
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Flies double mutant for otk2C26/otk2C26; fz19/fz19 are viable but exhibit planar polarity defects.

      (Linnemannstöns et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      otk2C26
      (Ripp et al., 2018, Linnemannstöns et al., 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)