FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\fra9YF.UAS.Tag:MYC
Open Close
General Information
Symbol
Dmel\fra9YF.UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0298359
Feature type
allele
Associated gene
Dmel\fra
Associated Insertion(s)
Carried in Construct
M{UAS-fra9YF-Myc}
Key Links
Transgenic product class
missense_variant
(O'Donnell and Bashaw, 2013)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(O'Donnell and Bashaw, 2013)
Mutagen
in vitro construct
(O'Donnell and Bashaw, 2013)
Progenitor genotype
Carried in construct
M{UAS-fra9YF-Myc}
Cytology
Description

10xUAS regulatory sequences drive expression of the fra coding sequence, in which all nine of the cytoplasmic tyrosines have been mutated (amino acid replacements Y1113F, Y1170F, Y1189F, Y1193F, Y1207F, Y1212F, Y1247F, Y1250F, and Y1313F). The coding sequence is tagged at the C-terminal with six copies of Tag:MYC.

(O'Donnell and Bashaw, 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
fra
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      fra9YF.UAS.Tag:MYC/Scer\GAL4elav.PLu rescues fra3/fra4

      (O'Donnell and Bashaw, 2013)

      fra9YF.UAS.Tag:MYC/Scer\GAL4elav.PLu rescues fra3

      (O'Donnell and Bashaw, 2013)
      Comments

      Expression of fra9YF.Scer\UAS.T:Hsap\MYC in all neurons, through expression under the control of Scer\GAL4elav.PLu, fully rescues fra3 commissural axon defects.

      Expression of fra9YF.Scer\UAS.T:Hsap\MYC in all neurons, through expression under the control of Scer\GAL4elav.PLu, rescues EW midline crossing defects in fra3/fra4 mutants.

      (O'Donnell and Bashaw, 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      fra9YF.Scer\UAS.T:Hsap\MYC
      fra9YF.UAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)