FB2026_02 , released June 18, 2026
Allele: Dmel\ft61
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General Information
Symbol
Dmel\ft61
Species
D. melanogaster
Name
FlyBase ID
FBal0298388
Feature type
allele
Associated gene
Dmel\ft
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Bosch et al., 2014)
Progenitor genotype
Cytology
Description

Amino acid replacement: T4854I.

(Bosch et al., 2014)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:4,200,015..4,200,015 [-]
Nucleotide change:

C4200015T

Amino acid change:

T4854I | ft-PA

Reported amino acid change:

T4854I

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Bosch et al., 2014)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adult eyes containing ft61 clones are larger and contain more mutant tissue than controls.

      ft8/ftG-rv and ft8/ft61 imaginal discs are larger and have more folds than controls.

      (Bosch et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      ft8/ft61 has imaginal disc phenotype, suppressible by Scer\GAL4αTub84B.PL/Fbxl7UAS.Tag:FLAG

      (Bosch et al., 2014)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Scer\GAL4αTub84B.PL-mediated expression of Fbxl7Scer\UAS.T:Zzzz\FLAG suppresses ft8/ft61 phenotypes, resulting in viable flies.

      (Bosch et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      fat61
      (Bosch et al., 2014)
      ft61
      (Matakatsu and Fehon, 2024)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)