FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\NimC4ΔNIM3-4.UAS.GFP
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General Information
Symbol
Dmel\NimC4ΔNIM3-4.UAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0299099
Feature type
allele
Associated gene
Dmel\NimC4
Associated Insertion(s)
Carried in Construct
P{UAS-NimC4-GFP.ΔNIM3-4}
Key Links
Transgenic product class
inframe_deletion
(Shklyar et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Shklyar et al., 2013)
Mutagen
in vitro construct
(Shklyar et al., 2013)
Progenitor genotype
Carried in construct
P{UAS-NimC4-GFP.ΔNIM3-4}
Cytology
Description

UASt regulatory sequences drive expression of a mutant form of NimC4 lacking the NIM3 and NIM4 domains, tagged at the C-terminal end with GFP.

(Shklyar et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
NimC4
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      NimC4ΔNIM3-4.UAS.GFP/Scer\GAL4repo fails to rescue NimC4KO

      (Shklyar et al., 2013)
      Comments

      Expression of NimC4ΔNIM3-4.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4repo does not rescue the defects in the engulfment of apoptotic neurons seen in the CNS of NimC4KO mutant embryos. The glial membranes appear normal in these flies.

      (Shklyar et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      NimC4ΔNIM3-4.Scer\UAS.T:Avic\GFP
      NimC4ΔNIM3-4.UAS.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (2)