FB2026_03 , released September 17, 2026
Allele: Dmel\CycJHZ14
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General Information
Symbol
Dmel\CycJHZ14
Species
D. melanogaster
Name
FlyBase ID
FBal0299630
Feature type
allele
Associated gene
Dmel\CycJ
Associated Insertion(s)
Carried in Construct
P{HZ14.CycJ}
Key Links
Transgenic product class
genomic_DNA
(Atikukke et al., 2014)
wild_type
(Atikukke et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Atikukke et al., 2014)
wild_type
(Atikukke et al., 2014)
Mutagen
in vitro construct
(Atikukke et al., 2014)
Progenitor genotype
Carried in construct
P{HZ14.CycJ}
Cytology
Description

A 4kb genomic fragment that encompasses CycJ (extends from 1.1kb upstream of the ATG to 1.9kb downstream of the stop codon, and includes the last exon of the upstream armi gene; a frameshift has been introduced to eliminate any armi coding potential).

(Atikukke et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
CycJ
Encoded product / tool
CycJ
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      Expression of CycJHZ14 significantly rescues the oogenesis defects seen in homozygous Df(3L)armi-J females. Females are capable of producing fully developed stage 14 egg chambers and of laying eggs, albeit at a dramatically reduced rate compared to heterozygotes. There is also a dramatic decrease in the frequency of compound egg chambers (multiple cysts in one follicular epithelium) when CycJHZ14 is expressed in Df(3L)armi-J/Df(3L)Exel6095.

      (Atikukke et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      CycJHZ14
      Name Synonyms
      Secondary FlyBase IDs
        References (1)