FlyBase Gene Report: Dmel\CycJ

General Information

Symbol

Dmel\CycJ

Species

D. melanogaster

Name

Cyclin J

Annotation Symbol

CG10308

Feature Type

protein_coding_gene

FlyBase ID

FBgn0010317

Gene Model Status

Current

Stock Availability

11 publicly available

Gene Summary

Cyclin J (CycJ) encodes a cyclin-dependent protein serine/threonine kinase regulator that contributes to oogenesis and the early embryonic division cycles. [Date last reviewed: 2019-09-19] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
Interactive Fly

Also Known As

Cdi5

Key Links

Genomic Location

Cytogenetic map

63E1-63E1

Sequence location

3L:3,466,428..3,468,098 [+]

Recombination map

3-8

RefSeq locus

NT_037436 REGION:3466428..3468098

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

Gene Ontology (GO) Annotations (9 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

enables cyclin-dependent protein serine/threonine kinase regulator activity

inferred from direct assay

(Finley et al., 1996)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables cyclin-dependent protein serine/threonine kinase regulator activity

inferred from biological aspect of ancestor with PANTHER:PTN000019791

(GO Reference Genome Project, 2011-)

Biological Process (4 terms)

Terms Based on Experimental Evidence (3 terms)

CV Term

Evidence

References

involved_in germarium-derived egg chamber formation

inferred from genetic interaction with FLYBASE:aub; FB:FBgn0000146

(Atikukke et al., 2014)

inferred from genetic interaction with FLYBASE:piwi; FB:FBgn0004872

(Atikukke et al., 2014)

involved_in mitotic cell cycle, embryonic

inferred from mutant phenotype

(Kolonin and Finley, 2000)

involved_in mitotic cell cycle

inferred from mutant phenotype

(Kolonin and Finley, 2000)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

involved_in G1/S transition of mitotic cell cycle

inferred from biological aspect of ancestor with PANTHER:PTN000019791

(GO Reference Genome Project, 2011-)

Cellular Component (4 terms)

Terms Based on Experimental Evidence (0 terms)

Terms Based on Predictions or Assertions (4 terms)

CV Term

Evidence

References

part_of cyclin-dependent protein kinase holoenzyme complex

inferred from biological aspect of ancestor with PANTHER:PTN000019791

(GO Reference Genome Project, 2011-)

is_active_in cytoplasm

inferred from biological aspect of ancestor with PANTHER:PTN000019791

(GO Reference Genome Project, 2011-)

is_active_in microtubule organizing center

inferred from biological aspect of ancestor with PANTHER:PTN007424001

(GO Reference Genome Project, 2011-)

is_active_in nucleus

inferred from biological aspect of ancestor with PANTHER:PTN000019791

(GO Reference Genome Project, 2011-)

Gene Group (FlyBase)

Protein Family (UniProt)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

Cyclin J (CycJ) encodes a cyclin-dependent protein serine/threonine kinase regulator that contributes to oogenesis and the early embryonic division cycles. [Date last reviewed: 2019-09-19]

Summary (Interactive Fly)

regulates S phase early in embryonic development, partners Cdk2 - strong genetic interactions between CycJ and piRNA pathway genes reveal a role for CycJ in early oogenesis

Interactive Fly

Gene Model and Products

Number of Transcripts

Number of Unique Polypeptides

Please see the JBrowse view of Dmel\CycJ for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9VZP3)

If you don't see a structure in the viewer, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures

Crossreferences

Comments on Gene Model

Gene model reviewed during 5.50

Gene model reviewed during 5.44

Gene model reviewed during 5.41

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.55

Multiphase exon postulated: exon reading frame differs in alternative transcripts; overlap >20aa.

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

CycJ-RA

FBtr0073127

NM_079179

1478

386

CycJ-RB

FBtr0073128

NM_206267

1471

261

Additional Transcript Data and Comments

Reported size (kB)

1.6 (northern blot)

(Finley et al., 1996)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

UniProt

RefSeq ID

GenBank

CycJ-PA

FBpp0072987

45.1

386

6.51

FBpp0089168

30.8

261

9.07

Q95U62

NP_995989

AAS64959

Polypeptides with Identical Sequences

None of the polypeptides share 100% sequence identity.

Additional Polypeptide Data and Comments

Reported size (kDa)

50 (kD observed)

(Kolonin and Finley, 2000)

391 (aa)

(Finley et al., 1996)

Comments

External Data

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Nucleotide / Polypeptide Records

UniProt

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CycJ using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

CycJ_1

Linkouts

Expression Data

Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

-0.23

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

pole plasm

Comment: maternally deposited

(Fisher et al., 2012)

organism

• pole plasm

Comment: maternally deposited

(Fisher et al., 2012)

embryonic stage 4 -- 6

organism

Comment: rapidly degraded

(Fisher et al., 2012)

primordial germ cell

(Fisher et al., 2012)

embryonic stage 7 -- 8

primordial germ cell

(Fisher et al., 2012)

northern blot

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 17

organism

(Finley et al., 1996)

adult stage | female

(Finley et al., 1996)

Additional Descriptive Data

CycJ is maternally expressed. It is detected only in adult females and early embryos.

(Finley et al., 1996)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

western blot

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 6

Comment: reference states 0-3 hr AEL

(Kolonin and Finley, 2000)

embryonic cycle 1 -- embryonic cycle 10

(Kolonin and Finley, 2000)

embryonic stage 4

(Kolonin and Finley, 2000)

adult stage | female

nurse cell

(Kolonin and Finley, 2000)

unfertilized egg stage

unfertilized egg

(Kolonin and Finley, 2000)

Additional Descriptive Data

CycJ protein is detected at high levels in the early embryo, during the first 10 nuclear cycles, but levels decline sharply thereafter. The protein is detected in the ovarian nurse cell cytoplasm in adult females, and is not detected in testes.

(Kolonin and Finley, 2000)

Marker for

Subcellular Localization

CV Term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\CycJ in JBrowse

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\CycJ

View exonic expression by tissue for Dmel\CycJ

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0010317

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

38428/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0010317

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0010317

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0010317

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG10308

Flygut - An atlas of the Drosophila adult midgut

FBgn0010317

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\CycJ

Stages(s) 1-3
Stages(s) 7-8

FlyBase Wiki

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 3 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 15 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of CycJ

Transgenic constructs containing regulatory region of CycJ

Aberrations (Deficiencies and Duplications) ( 4 )

Inferred from experimentation ( 4 )

Gene disrupted in

Df(3L)AJ14

(Althoff et al., 2009)

Df(3L)armi^Δ1

(Olivieri et al., 2010)

Df(3L)armi-J

(Atikukke et al., 2014)

Df(3L)Exel6095

(Althoff et al., 2009, Ryder, 2004.4.26)

Inferred from location ( 5 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

partially lethal, with Scer\GAL4^tin.CΔ4

CycJ^GD6936

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

CycJ^GD6936

viable, with Scer\GAL4^Mef2.PR

CycJ^GD6936

viable, with Scer\GAL4^pnr-MD237

CycJ^GD6936

Sterility

Allele

female semi-sterile (with Df(3L)Exel6095), with armi^+t6.3

CycJ^null

Other Phenotypes

Allele

abnormal immune response | adult stage

CycJ^GD6936

some die during pupal stage, with Scer\GAL4^tin.CΔ4

CycJ^GD6936

Phenotype manifest in

Allele

adult anterior midgut epithelium | conditional, with Scer\GAL4^NP3084

CycJ^GD6936

dorsal appendage, with armi^null

CycJ^+t4

egg, with armi^null

CycJ^+t4

egg chamber, with armi^null

CycJ^+t4

oocyte, with armi^null

CycJ^+t4

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Homo sapiens (Human) (19)

Hsap\CCNJL

9 of 14

Yes

Hsap\CCNJ

8 of 14

Yes

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Rattus norvegicus (Norway rat) (18)

Rnor\Ccnjl

9 of 14

Yes

Rnor\Ccnj

8 of 14

Yes

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

Yes

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Yes

Mus musculus (laboratory mouse) (17)

Mmus\Ccnjl

9 of 14

Yes

Mmus\Ccnj

8 of 14

Yes

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Xenopus tropicalis (Western clawed frog) (28)

Xtro\ccnj

5 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

1 of 13

Yes

1 of 13

1 of 13

1 of 13

1 of 13

Yes

Xtro\LOC101730848

1 of 13

Xtro\LOC105946681

1 of 13

Xtro\LOC105948062

1 of 13

Yes

Xtro\LOC105948063

1 of 13

Yes

Xtro\tm4sf4

1 of 13

Yes

Xtro\XB940382

1 of 13

Yes

Xtro\XB997834

1 of 13

Xtro\zmpste24

1 of 13

Danio rerio (Zebrafish) (20)

Drer\ccnjl

10 of 14

Yes

Drer\ccnj

8 of 14

Yes

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

1 of 14

Caenorhabditis elegans (Nematode, roundworm) (17)

Cele\cya-1

3 of 14

Yes

Cele\cyb-1

3 of 14

Yes

Cele\cyb-2.1

3 of 14

Yes

Cele\cyb-2.2

3 of 14

Yes

2 of 14

2 of 14

2 of 14

2 of 14

2 of 14

Yes

Cele\T24A6.1

2 of 14

Cele\W05G11.2

2 of 14

Yes

Cele\ZK678.3

2 of 14

Yes

Cele\C02B8.1

1 of 14

Yes

Cele\C03B8.2

1 of 14

Yes

Cele\C04C3.4

1 of 14

Yes

Cele\cyd-1

1 of 14

Cele\R02F2.1

1 of 14

Yes

Anopheles gambiae (African malaria mosquito) (8)

Agam\AgaP_AGAP002532

10 of 12

Yes

3 of 12

3 of 12

3 of 12

3 of 12

2 of 12

2 of 12

1 of 12

Arabidopsis thaliana (thale-cress) (33)

Atha\AT1G20590

4 of 13

Yes

Atha\CYC1BAT

4 of 13

Yes

Atha\CYC3B

4 of 13

Yes

Atha\CYCA1;1

4 of 13

Yes

Atha\CYCA1;2

4 of 13

Yes

Atha\CYCA2;1

4 of 13

Yes

Atha\CYCA2;3

4 of 13

Yes

Atha\CYCA2;4

4 of 13

Yes

Atha\CYCA3;1

4 of 13

Yes

Atha\CYCA3;2

4 of 13

Yes

Atha\CYCA3;3

4 of 13

Yes

Atha\CYCA3;4

4 of 13

Yes

Atha\CYCB1;1

4 of 13

Yes

Atha\CYCB1;3

4 of 13

Yes

Atha\CYCB1;4

4 of 13

Yes

Atha\CYCB2;1

4 of 13

Yes

Atha\CYCB2;2

4 of 13

Yes

Atha\CYCB2;3

4 of 13

Yes

Atha\CYCB2;4

4 of 13

Yes

Atha\CYCB3;1

4 of 13

Yes

Atha\CYCB1;5

3 of 13

Atha\SDS

3 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

1 of 13

Yes

Saccharomyces cerevisiae (Brewer's yeast) (9)

Scer\CLB1

3 of 13

Yes

Scer\CLB2

3 of 13

Yes

Scer\CLB5

3 of 13

Yes

Scer\CLB6

3 of 13

Yes

2 of 13

2 of 13

2 of 13

2 of 13

2 of 13

Schizosaccharomyces pombe (Fission yeast) (5)

Spom\puc1

4 of 12

Yes

3 of 12

3 of 12

2 of 12

2 of 12

Escherichia coli (enterobacterium) (0)

Other Organism Orthologs (via OrthoDB)

Data provided directly from OrthoDB:CycJ. Refer to their site for version information.

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v9.1)

Gene Symbol

Score

Source

Alignment

Drosophila melanogaster (Fruit fly) (6)

4 of 13

4 of 13

4 of 13

4 of 13

2 of 13

2 of 13

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Allele

Disease

Interaction

References

CycJ^GD6936

exacerbates Machado-Joseph disease

modeled by Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}

(Voßfeldt et al., 2012)

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

9 of 14

8 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

3 of 14

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

CycJ - Cdk1

anti tag coimmunoprecipitation, Identification by mass spectrometry, anti tag western blot, western blot

(Althoff et al., 2009)

CycJ - Cdk2

two hybrid

(Finley et al., 1996)

Summary of Genetic Interactions

Interaction Browsers

View in FlyBase Interactions Browser View in MIST tool (external link)

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

CycJ|armi

suppressible

lok

(Atikukke et al., 2014)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

piwi

enhanceable

CycJ|armi

(Atikukke et al., 2014)

External Data

Linkouts

BioGRID - A database of protein and genetic interactions.

63921

DroID - A comprehensive database of gene and protein interactions.

FBgn0010317

MIST (protein-protein) - An integrated Molecular Interaction Database

38428

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyBase

External Links

External Data

Linkouts

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

Q24159

Class of Gene

nuclear_gene

protein_coding_gene

Genomic Location and Detailed Mapping Data

Chromosome (arm)

Recombination map

3-8

Cytogenetic map

63E1-63E1

Sequence location

3L:3,466,428..3,468,098 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

63E1-63E1

Limits computationally determined from genome sequence between P{PZ}kst⁰¹³¹⁸ and P{PZ}Sc2⁰⁵⁶³⁴

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

63D2-63D3

(determined by in situ hybridisation)

(BDGP Project Members, 1994-1999)

Experimentally Determined Recombination Data

Location

3-8

(FlyBase, 2016)

3-6.9

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (11)

Aberrations including deletions of this gene Aberrations including duplications of this gene

Bloomington

91680

w^*; P{gEGFP-CycJ}III.16

91681

w^*; P{gCycJ-EGFP}III.12

91678

w^*; P{UAS-CycJ-EGFP}II.2

91679

w^*; P{UAS-EGFP-CycJ}II.1

85937

y¹ v¹; P{SAM.dCas9.GS05556}attP40

16049

y¹ w¹¹¹⁸; PBac{5HPw⁺}CycJ^A138

37521

y¹ sc^* v¹ sev²¹; P{TRiP.HMS01663}attP40

10308R-1

v110222

v31216

w¹¹¹⁸; P{GD6936}v31216

v341698

P{hsFLP}1, y¹ w¹¹¹⁸; P{HD_CFD00803}attP40/CyO-GFP

Genomic Clones (21)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (74)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

GH04281

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0010317

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

LD46761

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0010317

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Kolonin and Finley, 2000)

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

CycJ binds to cdc2 and not cdc2c.

(Althoff et al., 2009)

CycJ-deficient females with only one functional gene copy of CycA, CycB, CycB3 or CycE have a very similar fertility as those with two functional copies.

(Althoff et al., 2009)

dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R⁺ cell morphology.

(Kiger et al., 2003)

CycJ is required for the early embryonic division cycles.

(Kolonin and Finley, 2000)

Isolated by interaction with cdc2 and cdc2c using the interaction trap two hybrid system.

(Finley et al., 1996)

Yeast two-hybrid system has been used to characterise Cyclin-dependent kinase interactor proteins (the prey) in hunts with either cdc2 or cdc2c as baits. CycJ interacts with cdc2c and Cks30A, and S.cerevisiae cyclin-dependent kinase to activate transcription of a reporter gene, Ecol\lacZ.

(Finley and Brent, 1994)

The yeast interaction trap selection has been used to isolate cell cycle regulatory proteins that interact with cdc2 and cdc2c. CycJ interacts preferentially with cdc2c.

(Finley and Brent, 1993)

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Source for identity of: CycJ CG10308

(Yao, 1999.11)

Nomenclature comments

Etymology

Synonyms and Secondary IDs (10)

Reported As

Symbol Synonym

CDI5

(Finley and Brent, 1993)

CG10308

(Hosono et al., 2015, Voßfeldt et al., 2012, Ni et al., 2011.7.19, Keleman et al., 2009.8.5)

Cdi5

(Zhong et al., 2003, Finley et al., 1996)

CycJ

(Transgenic RNAi Project members, 2017-, Lee et al., 2016, Atikukke et al., 2014, Japanese National Institute of Genetics, 2012.5.21, Soshnev et al., 2012, Voßfeldt et al., 2012, Olivieri et al., 2010, Swaminathan et al., 2010, Stanyon et al., 2004)

cdi5

cycJ

(Kolonin and Finley, 2000)

cyclinJ

(Li and White, 2003)

Name Synonyms

Cyclin J

(Felix et al., 2012, Althoff et al., 2009, Atikukke and Finley, 2008, Atikukke and Finley, 2007)

Cyclin-dependent kinase interactor 5

cyclin J

(Atikukke and Finley, 2008)

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 46 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

38428

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9VZP3

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9VZP3

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0010317

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

38428/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0010317

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0010317

FlyMine - An integrated database for Drosophila genomics

FBgn0010317

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

dme:Dmel_CG10308

MARRVEL_MODEL - MARRVEL (model organism gene)

38428

Linkouts

BioGRID - A database of protein and genetic interactions.

63921

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0010317

DroID - A comprehensive database of gene and protein interactions.

FBgn0010317

DRSC - Results frm RNAi screens

FBgn0010317

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

CycJ_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0010317

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0010317

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

CG10308

Flygut - An atlas of the Drosophila adult midgut

FBgn0010317

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC031314

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

MIST (protein-protein) - An integrated Molecular Interaction Database

38428

SignaLink - A signaling pathway resource with multi-layered regulatory networks.

Q24159

References (59)

The following external sites may use different assemblies or annotations than FlyBase.

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