FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

cyclin-dependent protein kinase holoenzyme complex

ID (Ontology)

GO:0000307 (Gene Ontology)

Definition

Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner.[ PubMed:11602261 ]

Also Known As

"CDK holoenzyme"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
cyclin-dependent protein kinase holoenzyme complex (all annotations which use CV term, excluding "NOT" statements)
part_of \| cyclin-dependent protein kinase holoenzyme complex

Spanning Tree (Parents/Children)

  protein kinase complex
   |__serine/threonine protein kinase complex
       |__cyclin-dependent protein kinase holoenzyme complex  40 rec.
           |__cyclin A1-CDK1 complex
           |__cyclin A1-CDK2 complex
           |__cyclin A2-CDK1 complex
           |__cyclin A2-CDK2 complex 1 rec.
           |__cyclin B1-CDK1 complex
           |__cyclin B2-CDK1 complex
           |__cyclin B3-CDK2 complex
           |__cyclin D1-CDK4 complex
           |__cyclin D1-CDK6 complex
           |__cyclin D2-CDK4 complex
           |__cyclin D2-CDK6 complex
           |__cyclin D3-CDK4 complex
           |__cyclin D3-CDK6 complex
           |__cyclin E1-CDK2 complex 1 rec.
           |__cyclin E2-CDK2 complex
           |__cyclin K-CDK12 complex 1 rec.
           |__cyclin K-CDK13 complex
           |__cyclin L-CDK11 complex
           |__cytoplasmic cyclin-dependent protein kinase holoenzyme complex
           |__MPF complex
           |__nuclear cyclin-dependent protein kinase holoenzyme complex 24 rec.
           |   |__CKM complex 6 rec.
           |   |__cyclin/CDK positive transcription elongation factor complex(+) 5 rec.
           |   |__transcription factor TFIIH holo complex(+) 13 rec.
           |__Pho85-Pho80 CDK-cyclin complex

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	serine/threonine protein kinase complex
Part of
Synonyms & Secondary IDs
Synonyms
	"CDK holoenzyme" EXACT
Secondary IDs

External Crossreferences & Linkouts