FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Adi174
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General Information
Symbol
Dmel\Adi174
Species
D. melanogaster
Name
FlyBase ID
FBal0299774
Feature type
allele
Associated gene
Dmel\Adi1
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Chou et al., 2014)
Mutagen
Delta2-3 transposase
(Chou et al., 2014)
Progenitor genotype
P{XP}Adi1d01129
(Chou et al., 2014)
Cytology
Description

Imprecise excision of the progenitor insertion resulting in deletion of the Adi1 gene from 3L:10656504 to 3L:10657550 (release 5 coordinates), which encompasses the entire coding region.

(Chou et al., 2014)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3L:10,663,404..10,664,450 [+]
Comment:

A deletion resulting from imprecise excision of P{XP}Adi1d01129 that maps to 3L:10656504..10657550 in release 5 coordinates.

(Chou et al., 2014)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Lethality of homozygotes is less than 5%.

      Under a restricted diet condition, but not under fully fed conditions, mutant females display a significant reduction in fecundity compared to controls.

      (Chou et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      Adi174 has female semi-fertile | nutrition conditional phenotype, suppressible by Scer\GAL4Act.PU/Hsap\ADI1WT.UAS

      (Chou et al., 2014)
      NOT suppressed by
      Statement
      Reference

      Adi174 has female semi-fertile | nutrition conditional phenotype, non-suppressible by Scer\GAL4Act.PU/Hsap\ADI1E94A.UAS

      (Chou et al., 2014)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescued by

      Adi174 is partially rescued by Scer\GAL4Act.PU/Adi1UAS.cCa

      (Chou et al., 2014)
      Comments

      Scer\GAL4Act.PU-mediated expression of Adi1Scer\UAS.cCa partially rescues the fecundity defect of Adi174 females.

      (Chou et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Adi174
      Dadi174
      (Chou et al., 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)