FB2026_03 , released September 17, 2026
Allele: Dmel\Arl12
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General Information
Symbol
Dmel\Arl12
Species
D. melanogaster
Name
FlyBase ID
FBal0300956
Feature type
allele
Associated gene
Dmel\Arl1
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
    Nature of the Allele
    Allele class

    amorphic allele - molecular evidence

    (Torres et al., 2014)
    Mutagen
    Progenitor genotype
    Cytology
    Description

    A frameshift mutation that truncates the protein after only 14 amino acids.

    (Torres et al., 2014)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Arl12/Arl11 or Arl12/Df(3L)brm11 larval salivary glands have more secretory granules of significantly smaller size, compared to controls.

        (Torres et al., 2014)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        Arl11/Arl12 is rescued by Arl1+t2.5

        (Torres et al., 2014)
        Comments

        Arl1+t2.5 rescues the secretory granule defects in Arl12/Arl11 salivary glands.

        (Torres et al., 2014)
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer

        Associated with: A very close second lethal mutation that could not be recombined away.

        (Torres et al., 2014)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        Arl12
        arl12
        (Torres et al., 2014)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)