FB2026_02 , released June 18, 2026
Allele: Dmel\IscU115
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General Information
Symbol
Dmel\IscU115
Species
D. melanogaster
Name
FlyBase ID
FBal0301097
Feature type
allele
Associated gene
Dmel\IscU
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Tian et al., 2014)
Progenitor genotype
P{SUPor-P}KG01476
(Tian et al., 2014)
Cytology
Description

Imprecise excision of the progenitor P{SUPor-P}KG01476 insertion, resulting in a deletion that removes most of IscU.

(Tian et al., 2014)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      IscU115 homozygotes carrying IscUS20E survive only to the third larval instar stage.

      IscU115 flies carrying IscUS20A are more sensitive to oxidative stress (either 10mM paraquat or 2% hydrogen peroxide) compared to controls.

      (Tian et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescued by

      IscU115 is partially rescued by IscUS20A

      (Tian et al., 2014)
      Comments

      IscU115 homozygotes carrying IscUS20A are viable and have no visible morphological or developmental abnormalities.

      (Tian et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CG9836115
      (Tian et al., 2014)
      IscU115
      iscu115
      (Tian et al., 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)