FB2026_02 , released June 18, 2026
Allele: Dmel\LrrkHA
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General Information
Symbol
Dmel\LrrkHA
Species
D. melanogaster
Name
FlyBase ID
FBal0301551
Feature type
allele
Associated gene
Dmel\Lrrk
Associated Insertion(s)
TI{TI}LrrkHA
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
phiC31 integrase
(Vilain et al., 2014)
I-CreI
(Vilain et al., 2014)
I-SceI
(Vilain et al., 2014)
gene targeting by homologous recombination
(Vilain et al., 2014)
Progenitor genotype
Mi{MIC}GluRIIEMI01886
(Vilain et al., 2014)
Associated Insertion(s)
TI{TI}LrrkHA
Cytology
Description

A triple Tag:HA tag has been inserted into the endogenous Lrrk locus, at the C-terminal end of the open reading frame. This was achieved by phiC31:int-mediated integration of a recombination cassette to replace the RMCE cassette present in the Mi{MIC}GluRIIEMI01886 insertion, followed by two consecutive homologous recombination steps induced using the RS(I-SceI) site and then the RS(I-CreI) site that were each present in the inserted recombination cassette.

(Vilain et al., 2014)
Allele components
Component
Use(s)
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      LRRKHA
      (Vilain et al., 2014)
      LrrkHA
      (Sarkar et al., 2021, Bardai et al., 2018)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)