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General Information
Symbol
Dmel\sickK1881A.UAS.mCherry
Species
D. melanogaster
Name
FlyBase ID
FBal0301625
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of a mutant form of sick, in which the lysine at amino acid 1881 has been replaced by alanine, tagged at the N-terminal end with mCherry.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Suppressor of
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Expression of sickK1881A.Scer\UAS.T:Disc\RFP-mCherry does not suppress the axon growth defect and F-actin elevation seen in the α/β mushroom body lobes when LIMK1Scer\UAS.T:Ivir\HA1 is expressed under the control of Scer\GAL4ey-OK107.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Expression of sickK1881A.Scer\UAS.T:Disc\RFP-mCherry under the control of Scer\GAL4ey-OK107 fails to rescue the axonal growth defects seen in the α/β mushroom body lobes of sickΔ/sickA384 mutants.

Expression of sickK1881A.Scer\UAS.T:Disc\RFP-mCherry under the control of Scer\GAL4NP7175 fails to rescue the axonal growth defects seen in the α/β mushroom body lobes of sickΔ/sickA384 mutants.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
sickK1881A.Scer\UAS.T:Disc\RFP-mCherry
sickK1881A.UAS.mCherry
Name Synonyms
Secondary FlyBase IDs
    References (1)