FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\FASN1UAS.cGa
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General Information
Symbol
Dmel\FASN1UAS.cGa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Garrido
FlyBase ID
FBal0303674
Feature type
allele
Associated gene
Dmel\FASN1
Associated Insertion(s)
Carried in Construct
P{UAS-FASN1.G}
Also Known As
UAS-Fasn1
Key Links
Transgenic product class
wild_type
(Garrido et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Garrido et al., 2015)
Mutagen
in vitro construct
(Garrido et al., 2015)
Progenitor genotype
Carried in construct
P{UAS-FASN1.G}
Cytology
Description

UASt regulates expression of FASN1.

(Garrido et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
FASN1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of FASN1UAS.cGa under the control of Scer\GAL4GMR.PU does not affect receptor potential (measured by electroretinogram) in 10 d old adults, compared to controls.

      (Weigelt et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      FASN1UAS.cGa partially rescues Df(2L)FASNΔ24

      (Garrido et al., 2015)

      FASN1UAS.cGa partially rescues Df(2L)FASNΔ24-23

      (Garrido et al., 2015)
      Fails to rescue

      Scer\GAL4da.PU/FASN1UAS.cGa fails to rescue Df(2L)FASNΔ24

      (Garrido et al., 2015)

      Scer\GAL4da.PU/FASN1UAS.cGa fails to rescue Df(2L)FASNΔ24-23

      (Garrido et al., 2015)
      Comments

      Scer\GAL4da.PU-mediated expression of FASN1Scer\UAS.cGa does not rescue the lethality of Df(2L)FASNΔ24 or Df(2L)FASNΔ24-23 animals. However, one FASN1Scer\UAS.cGa line can partially rescue the lethal phenotype of Df(2L)FASNΔ24 or Df(2L)FASNΔ24-23 animals in the absence of a Scer\GAL4 driver.

      (Garrido et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      FASN1Scer\UAS.cGa
      FASN1UAS.cGa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Garrido
      Secondary FlyBase IDs
        References (3)